Fasting blood sugar lowering action of antiarrhythmic drug Disopyramide.

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Kv1.5 open channel block by the antiarrhythmic drug disopyramide: molecular determinants of block.

Kv1.5 is considered to be a potential molecular target for treatment of atrial fibrillation or flutter. Disopyramide is widely used in the treatment of atrial flutter and/or atrial fibrillation. The present study was undertaken to characterize the effects of disopyramide on currents mediated by Kv1.5 channels and to determine the putative binding site involved in the inhibitory effects of disop...

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ژورنال

عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics

سال: 1997

ISSN: 1882-8272,0388-1601

DOI: 10.3999/jscpt.28.477